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What is an example of therapeutic duplication that pharmacists should detect?

  1. Different medications with similar mechanisms of action

  2. Duplicate records in the patient's medication history

  3. Patients receiving insulin alongside oral hypoglycemics

  4. Patients who refuse to take prescribed medications

The correct answer is: Different medications with similar mechanisms of action

Therapeutic duplication occurs when a patient is prescribed multiple medications that serve the same therapeutic purpose or have similar mechanisms of action, which can increase the risk of adverse effects or toxicity without providing additional benefit. In this context, the correct response highlights the importance of identifying instances where different medications may be prescribed to treat the same condition, potentially leading to unnecessary complications. For example, if a patient is prescribed two different classes of medications that both lower blood pressure, the risk of hypotension increases without a proportional therapeutic gain. Pharmacists play a crucial role in medication management by reviewing patients' medication regimens for such duplications, ensuring that each medication serves a distinct purpose and that therapy is optimized safely. In contrast, the other options address scenarios that do not specifically involve therapeutic duplication. For example, duplicate records in a patient's medication history relate to documentation errors rather than medication therapy, and while insulin and oral hypoglycemics can be used together, they may be part of a carefully managed treatment plan rather than an instance of duplication. Furthermore, patient refusal to take prescribed medications speaks to adherence rather than therapeutic overlap. This demonstrates why understanding therapeutic duplication is essential for pharmacists to promote safe and effective medication use among patients.